The film takes a very strong position against suicide, and says that 15% of the adult population sometimes has suicidal thoughts. Willingness to deal with personal adversity and accept interdependence with others is seen as essential to "civilizing" the universe; random adversity is unavoidable. .
I would expect to have certain karma problems in the afterlife. I feel repelled by the idea of intimacy with people who are too much less than "perfect". My own having what is arguably a slight physical "disability" (and indeed ambiguous in my case) did not make me more "compassionate"; it made me more attached to personal meritocracy. Life is not a miracle when it engages my "emotional body" (a term in the film). Intellectually, I think that life, culminating in free will, is nature's way of managing entropy. Living things age because of entropy, so they must reproduce. The idea of a cycle of physical life and then spiritual life for any agent of Will would seem to sustain the Universe, from the viewpoint of cosmology.